The Bills have tried to follow the Eagles blueprint to beating Mahomes by beefing up their front four. They signed Joey Bosa in free agency this offseason, extended edge rusher Gregory Rousseau and used their first five draft picks on defense, including three along the defensive line ( T.J. Sanders, Landon Jackson, Deone Walker ).

Two of the best quarterbacks in the NFL face off for the 10th time in their careers in Week 9. Here's how the two compare entering this matchup.

Kansas City Chiefs quarterback Patrick Mahomes launches a 40-yard pass to Hollywood Brown against the Buffalo Bills.

The MVP race is wide open, with each member of the "FOX NFL Kickoff" crew picking a different frontrunner for MVP.

The NFL announced its decision on a potential punishment on a play involving Kansas City Chiefs quarterback Patrick Mahomes.

Even though the calendar says November, it's still the last day of Halloweekend with Halloween falling on Friday. So naturally, New England Patriots receiver Mack Hollins treated the pregame tunnel walk like another costume reveal.

National Football League fans worldwide know the narrative when it comes to the Kansas City Chiefs taking on the Buffalo Bills in the regular season: the Bills