An Upstate woman is the latest lottery winner in South Carolina. The woman, who did not want to be identified, bought the ...

Each week on WYFF News 4, we will introduce you to new businesses, activities, restaurants, events, etc. in the Upstate area ...

The South Carolina Department of Transportation has closed a bridge in Pickens County out of an "abundance of caution." ...

South Carolina State Senator Josh Kimbrell, who announced his candidacy for governor in June, will hold a news conference ...

At least one out of every five bridges in the Upstate owned and maintained by SCDOT is under a load restriction, according to the department's data.

Upstate Pride SC holds an annual LGBTQ+ march and festival each fall in Spartanburg. It might add a film festival and night ...

Authorities arrest Mayo Levord Pickens in Upstate SC, seizing over 165 pounds of cocaine and firearms from his residence ...

GREENVILLE, S.C. (FOX Carolina) - The South Carolina Education Lottery said a man from North Carolina bought a winning ...

According to the Centers for Disease Control and Prevention, 1,267 cases of measles had been confirmed in the U.S. as of July 1, 2025, including cases in Palmetto State neighbors Georgia and North ...

Desiree Gomez greets friends and family followed by her husband, Mohamad Shokair, at Greenville-Spartanburg International ...

The South Carolina Gamecocks play host to USC Upstate for a midweek matchup on Tuesday evening. Here's how to watch the matchup. The South Carolina Gamecocks baseball season hasn't exactly gone ...