In a 3-hour game, the San Francisco 49ers played about 10 minutes of good football as the Houston Texans dominated in every aspect of a 26-15 game that was nowhere near that close.

Instead of having to settle for another field goal, C.J, Stroud and Xavier Hutchinson hooked up to put the 49ers in a deeper hole.

The 49ers have played some bad football this season. But Sunday was something else entirely: The 49ers played so poorly against the Houston Texans that it makes you question if they can ever win again. Their performance in a 29-15 loss was, in a word, awful.

Houston Texans quarterback C.J. Stroud (7) is congratulated by teammates Aireontae Ersery (79) and Tytus Howard (71) after throwing a touchdown pass during the second half of an NFL football game against the San Francisco 49ers Sunday, Oct. 26, 2025, in Houston. Credit: AP/Eric Christian Smith

San Francisco 49ers cornerback Deommodore Lenoir intercepts Houston Texans quarterback C.J. Stroud to end the first half in the Week 8 matchup. This marks the 49ers first interception of the season.

Kickoff from NRG Stadium is set for 1 p.m. ET, and the Texans are 1.5-point favorites, according to the latest 49ers vs. Texans odds. The over/under for total points scored is 42. Before you make any Texans vs. 49ers picks, make sure to check out what the SportsLine Projection Model has to say.

The Texans came into Sunday having just played their worst offensive performance of the season. They had a season low 254 yards in their 27-19 loss to the Seattle Seahawks six days before, and they failed to score an offensive touchdown until their final possession.

San Francisco 49ers running back Brian Robinson Jr. displays blazing speed on a 46-yard kick return to set the 49ers up past the 50-yard against the Houston Texans.