These toxins damage the lining of the colon and can cause a significant infection. Even a short course of antibiotics may lead to a C. diff infection, especially in people with weakened immune systems ...

C. diff, short for Clostridioides difficile (formerly called Clostridum difficile), is a type of bacteria that can cause an infection in your colon, the longest part of your large intestine. In most ...

Affecting roughly half a million Americans each year, bacterial infections caused by Clostridioides difficile—commonly known as C. diff—are a serious and persistent problem for patients and hospitals ...

A novel vaccination approach developed by Vanderbilt Health researchers cleared the harmful gut bacterium Clostridioides difficile (C. diff) in an animal model of infection. An experimental vaccine ...

Why do nonsteroidal anti-inflammatory drugs (NSAIDs) exacerbate gastrointestinal infections by Clostridioides difficile, the leading cause of antibiotic-associated diarrhea worldwide? In a new paper ...

Study shows that NSAIDs disrupt epithelial cells in the colon and sensitize them to C. difficile toxins by perturbing cell mitochondria Prior studies have shown that NSAIDs like indomethacin, aspirin, ...

Newswise — Every time we take antibiotics—whether it’s for strep throat, urinary tract infections, or pneumonia —there is a slim chance that “bad” bacteria can move in and wreak havoc on our digestive ...

A new vaccine provides hope for treating and even preventing the highly contagious and difficult-to-treat Clostridioides difficile infection, more commonly known as C. difficile or C. diff. In animal ...

Q: I was sick for months with debilitating pain, extreme weight loss, fatigue and loss of appetite. I was diagnosed with C. diff related to an abdominal surgery. I’m being treated with antibiotics, ...

Dear Doctors: I was sick for months with debilitating pain, extreme weight loss, fatigue and loss of appetite. I was diagnosed with C. diff related to an abdominal surgery. I’m being treated with ...

The hospital-acquired infection Clostridium difficile, which causes inflammation of the colon and can be deadly among elderly patients, may be spread outside the hospital setting via food, according ...

A rise in life-threatening gut infections has prompted fresh warnings about the dangers of antibiotic overuse. Clostridioides difficile (C. diff) is a serious bacterial infection that can cause severe ...