BMJ Quality & Safety

Double trouble: a propensity-matched cohort study evaluating the associations between duplicate medical records and patient outcomes

Introduction Duplicate medical records occur when a single patient is assigned multiple medical record numbers within an ...
AHA/ASA Journals

Second- and Third-Generation BCR-ABL Tyrosine Kinase Inhibitors and the Risk of Pulmonary Arterial Hypertension: A Prevalent New-User Design

BACKGROUND: BCR-ABL tyrosine kinase inhibitors (TKIs) have been increasingly linked to pulmonary arterial hypertension (PAH) since 2009, although supporting evidence is limited. Our objective was to ...
ascopubs.org

Using Dose-Escalation and -Expansion Cohort Study as Pivotal Trial for Targeted Anticancer Drug Approval

BRCA1-Associated Protein 1 and Enhancer of Zeste Homolog 2: Pathway Interaction and Therapeutic Intervention in Breast Cancer, Mesothelioma, and Lymphoma Early-phase clinical trials (EPCTs) have been ...
ascopubs.org

Adaptive Cohort Size Determination Method for Bayesian Optimal Interval Phase I/II Design to Shorten Clinical Trial Duration

Improved Cancer-Specific Risk Stratification by the Lymph Node Ratio-Based Nomogram: A Potential Role in Guiding Postoperative Management Decisions for Oral Cavity Carcinoma We propose a novel ...
The American Journal of Managed Care

Adherence Patterns 1 Year After Initiation of SGLT2 Inhibitors: Results of a National Cohort Study

This article describes the trajectory of adherence patterns among users of sodium-glucose cotransporter 2 (SGLT2) inhibitors. The authors found that baseline factors were unable to predict the ...
Kaleido Scope

Risk Underlying Rural Areas Longitudinal Cohort Study (RURAL) Heart and Lung Study

The RURAL (Risk Underlying Rural Areas Longitudinal) Cohort Study is a 35 Million Dollar National Heart, Lung, and Blood Institute (NHLBI) funded longitudinal cohort study that aims to address ...