Table I shows the simulation results for predicted post-conversion VPA minimum concentration (C min), maximum concentration (C max) and the percentage of patients predicted to have plasma VPA C min ...
Dr. Gary J. Kennedy answers the question: 'Divalproex For Bipolar Disorder?' — -- Question: How is divalproex (Depakote) used in the treatment of bipolar disorder, and what are the side effects ...
Divalproex sodium 250mg, 500mg; ext-rel tabs. Divalproex sodium dissociates to the valproate ion in the gastrointestinal tract. The mechanisms by which valproate exerts its therapeutic effects have ...
Our computer simulations suggest that conventional divalproex administered q12h should be directly and immediately converted (no greater than a 12-hour gap) to 8-20% higher divalproex ER once-daily ...