Heat Shock Factor 1 (HSF1) is a pivotal transcription factor that orchestrates the cellular response to proteotoxic and various other forms of stress. By regulating a comprehensive transcriptional ...
From molecular chaperones to mitochondrial failure, discover how heat reshapes the human transcriptome and drives the biological cascade that links rising temperatures to organ injury and public ...
(L to R) Corresponding author Charalampos Babis Kalodimos, PhD, St. Jude Department of Structural Biology chair, and co-first authors Ziad Ibrahim and Youlin Xia, St. Jude Department of Structural ...
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