The first resource containing high-resolution DNA sequencing data for over 37,000 children and parents collected over multiple decades from across the UK is now available to researchers worldwide. The ...

DNA methylation is an epigenetic modification crucial to normal development, with its dysregulation leading to various diseases including cancer. As interest in epigenomics grows, an innovative ...

DNA-Points Accumulation for Imaging in Nanoscale Topography (DNA-PAINT) enables multiplexed super-resolution imaging of biological samples. We expand the repertoire of speed-optimized DNA-PAINT ...

Single-Molecule Localization Microscopy (SMLM) has traditionally faced challenges to optimize signal-to-noise ratio, penetration depth, field-of-view (FOV), and spatial resolution simultaneously. Here ...

Researchers at the Indian Institute of Science have advanced the DNA-PAINT microscopy technique to visualize up to 12 biomolecules inside a cancer cell nucleus at 3–5 nanometer resolution. The ...

Pictures of DNA often look very tidy—the strands of the double helix neatly wind around each other, making it seem like studying genetics should be relatively straightforward. In truth, these strands ...

A new analysis method can detect pathogens in blood samples faster and more accurately than blood cultures, which are the current state of the art for infection diagnosis. The new method, called ...

The binding of proteins to DNA is crucial for producing other proteins, ensuring that all the necessary processes in cells are performed, and for switching genes on or off. Proteins that bind to DNA ...

Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA – its genome – and segregate it equally ...

DNA methylation is a highly studied epigenetic modification that regulates genome function and plays key roles in development and disease 1. It is linked to a broad range of conditions, including ...

A study identifies TET2–GFI1 axis as a critical brake suppressing malignant transformation of hematopoietic stem cells in myelodysplastic syndromes Published on April 01, 2026, in Volume 2, article ...