T helper 17 (Th17) cells generate the pro-inflammatory cytokine interleukin-17 (IL17/IL17A). IL17 has been a target for a variety of therapeutic monoclonal antibodies and inhibitors to treat different ...

Increasing evidence suggests that IL-17A and Th17 cells play a major role in autoimmune inflammation, but there are gaps in our understanding of IL-17RA signaling mechanisms. IL-17RA is expressed in ...

Sanofi SA has synthesized interleukin-17A (IL-17A)/interleukin-17 receptor A (IL-17RA) interaction inhibitors reported to be useful for the treatment of psoriasis, rheumatoid arthritis, radiographic ...

This is part of a series of stories on inflammation triggered by SARS-CoV-2 infection. Other articles in the series include lectins, Covid-19 and brain injury, Covid-19 infection of monocytes, and ...