The authors have proposed the Microbiota-derived metabolites–epigenetics (MDME) axis, a conceptual framework explaining how ...
CorrectSequence Therapeutics' CS-121 Completed Dosing of First Chylomicronemia Patient, Demonstrating Excellent Safety and Significant Efficacy SHANGHAI, Nov. 5, 2025 /PRNewswire/ -- On November 6, ...
Our bodies follow a natural 24-hour cycle known as the circadian rhythm that influences everything from sleep to metabolism. While scientists have long known that certain core circadian clock genes ...
Bmal2 is a biological clock gene. In an article published in Metabolism, scientists show that mice with the Bmal2 gene ...
Liver cancer is a lethal disease with limited treatment options for advanced stages. While risk factors such as viral hepatitis, alcohol use, and obesity increase the likelihood of hepatocellular ...
Recent evidence highlights the complex interplay between the central nervous system and hepatic drug-metabolising enzymes. In particular, the regulation of liver cytochrome P450 (CYP) enzymes by ...
An overview of the role, mechanisms and therapeutic implications of lipid droplet perilipin 2 in liver diseases ...
The FDA has officially placed two of Intellia’s Phase III studies under clinical hold after the biotech reported earlier this ...
Intellia earlier this year reported a similar grade 4 liver enzyme elevation associated with the gene therapy nexiguran ...
Our bodies follow a natural 24-hour cycle known as the circadian rhythm that influences everything from sleep to metabolism. While scientists have long known that certain core circadian clock genes ...