Researchers identified OLE, a molecule derived from the PM20D1 gene, that reprograms microglia into a more protective state ...
A newly identified molecule called OLE helped restore the brain’s immune cells to a more protective state in Alzheimer’s ...
A new study finds that microglia with mutant TREM2 protein reduce brain circuit connections, promote inflammation and contribute to Alzheimer's pathology in other ways. A rare but potent genetic ...
A team of Japanese and German scientists said its recent discoveries could lead to medicine that promotes and prolongs ...
A new study, published today in Nature Communications, offers clues into how APOE isoforms differentially affect human microglia function in Alzheimer's disease. The study, led by Dr. Sarah Marzi and ...
In the search for answers about Alzheimer’s disease, researchers are taking a close look at the immune system of the brain. A new study uncovers how a key immune cell, called a microglia, might be the ...
Discovery that microglia can be effectively replaced could transform cell therapy for brain diseases
An international research team led by Professor Kiavash Movahedi from the Brussels Center for Immunology at the Vrije Universiteit Brussel has published unexpected results in the journal Immunity.
Researchers now want to understand if other environmental exposures impact microglia similarly, and whether these changes lead to long-term alterations in brain circuitry and function. Lowery, R.L., ...
Scientists reprogram brain immune cells to fight Alzheimer's: Study ...
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