NFL Week 13 odds, picks, predictions, TV channel, streaming information for the Sunday football game between San Francisco 49ers and Cleveland Browns.

We're diving into every matchup in Week 13 of the 2025 NFL season â?? including key storylines, matchups to watch, and injury news. The Green

Everything you need to know about the NFL match between Cleveland Browns and San Francisco 49ers, as well as kick-off time and team news

NFL regular season officially kicks off on Thursday, November 20, with a primetime AFC showdown between the Buffalo Bills and Houston Texans at NRG Stadium on Prime Video. Houston will be without star quarterback CJ Stroud for a third straight game as he remains in concussion protocol,

With a win tonight, the 49ers’ odds of making the playoffs move from 83 percent from 89 percent in The Athletic’s NFL Playoff Simulator. With the Rams firmly atop the NFC West (and, now, the entire NFC), San Francisco is overwhelmingly likely to make the playoffs as a wild-card team.

It's the San Francisco 49ers vs Carolina Panthers on Monday Night Football in Week 12 of the 2025 NFL season. Here's how to watch, including time, TV channel and streaming info.