Genome-wide association studies (GWAS) have uncovered thousands of risk variants that individually have small effects on the risk of human diseases, including chronic kidney disease, type 2 diabetes, ...

Prediction from polygenic scores may be confounded by sources of passive gene-environment correlation (rGE; e.g. population stratification, assortative mating, and environmentally mediated effects of ...

Three out of four U.S. adults support the use of emerging technologies that estimate a future child's likelihood of developing health conditions influenced by multiple genes - such as diabetes, heart ...

As predictive medicine advances, legal scholars warn that decades-old federal guidelines could set up a potential clash between your genes and your job. By Emily Baumgaertner Nunn Imagine this ...

Survey reveals nearly three-quarters of U.S. adults support using emerging technology to screen embryos during IVF for risk of developing certain health conditions or traits that arise from more than ...

The optimism is not unfounded. In specific, well-defined clinical scenarios, polygenic scores are beginning to demonstrate some tangible utility. For cardiovascular disease, MI-GENES, a 10-year follow ...

New genetic research shows a simple genetic test can predict who’s most at risk for obesity, offering hope for early prevention, but also raises tough questions about genetic fairness and healthcare ...

Please provide your email address to receive an email when new articles are posted on . More research is needed for preimplantation genetic testing for polygenic disorders. Now, it cannot account for ...

Cost-utility studies provide critical information for the costs and benefits of using any new test, typically building on existing public health and screening programmes, within a defined population.

Investigations of the genetic basis of coronary artery disease have led to advances in mechanistic insights, therapeutics, prevention, and risk prediction. Indeed, most contemporary medicines for ...