Patients with symptomatic acute hepatic porphyria were found to be at greater risk of accessing long-term sick leave and disability pension compared with the general population, but were not shown to ...

Diagnosing acute hepatic porphyria (AIP) involves measuring porphobilinogen (PBG) levels in urine during symptomatic episodes, combined with genetic testing to identify HMBS gene alterations that ...

Acute hepatic porphyria (AHP) refers to a family of rare genetic diseases that affect the production of heme, a component of red blood cells. It can cause life threatening complications. AHP can cause ...

AIP is a rare genetic disorder affecting heme production, leading to a buildup of porphyrin precursors that can trigger acute episodes. AIP symptoms can range from abdominal pain and nausea to nerve ...

Up-regulation of hepatic delta-aminolevulinic acid synthase 1 (ALAS1), with resultant accumulation of delta-aminolevulinic acid (ALA) and porphobilinogen, is central to the pathogenesis of acute ...

SOME of the manifestations of acute intermittent porphyria are suggestive of thyrotoxicosis. These include emotional lability, tachycardia and muscular weakness, and such findings have on occasion led ...