Amyloid precursor proteins (APPs) are evolutionarily conserved membrane glycoproteins that undergo complex proteolytic processing to yield fragments with diverse biological activities. Beyond their ...

A crucial ‘precursor’ has been identified in pathological protein fibril formation. Researchers from Tokyo Metropolitan University (Japan) have applied ideas from polymer physics to illuminate the ...

Care of patients with systemic immunoglobulin light chain (AL) amyloidosis has undergone transformative changes, leading to marked, steady progress in outcomes for patients over the past four decades.

Brain development is a highly orchestrated process involving numerous parallel and sequential steps. Many of these steps depend on the activation of specific genes. A team led by Christian Mayer at ...

Study reveals how proteins direct nerve cell precursors to turn into specialized neurons. Brain development is a highly orchestrated process involving numerous parallel and sequential steps. Many of ...

A research group at Uppsala University has demonstrated that a new method for PET imaging of Alzheimer's disease is effective. The study was conducted in collaboration between the Department of Public ...