You may not be aware that most of the medicines that have been approved for treatment are rooted in nature. For example, the bark of willow trees has been called nature's aspirin because it contains a ...
A team of chemists has unveiled a novel method to simplify the synthesis of piperidines, a key structural component in many pharmaceuticals. The study combines biocatalytic carbon-hydrogen oxidation ...
A blue macrocyclic peptide binds a yellow protein. Enlicitide binds to PCSK9 to lower cholesterol. Credit: Merck & Co. “What this paper illustrates is the incredible power of biocatalysis to ...
A University of Texas at Dallas chemist and his colleagues have developed a new chemical reaction that will allow researchers to synthesize selectively the left-handed or right-handed versions of ...
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A drug discovery bottleneck? How cheaper reagents could speed branched molecule synthesis
When chemists design drug candidates, shape matters enormously. Many active pharmaceutical ingredients contain branched carbon structures—points where the molecular chain forks in a specific direction ...
Hans Renata and Kenta Yokoi in Renata’s lab at Rice (Credit: Alex Becker/Rice University). A team of chemists from Scripps Research and Rice University has unveiled a novel method to simplify the ...
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