The global pandemic may be over, but SARS-CoV-2 continues to infect people around the world. Indeed, the United States has recorded roughly 750 deaths from COVID-19 over the past month. Now, an siRNA ...

UCSF researchers designed new drug candidates that potently block MPro, a viral enzyme that's crucial for SARS-CoV-2 replication. One of these drug candidates, AVI-4516, is shown (center) bound to the ...

Researchers have discovered that SARS-CoV-2, the virus that causes COVID-19, may be changing crucial white blood cells called neutrophils so that instead of working to destroy pathogens, they instead ...

Drug discovery requires two separate steps: checking whether a drug can bind to a harmful molecule or its receptor, and finding out if the drug can stop the molecule and its receptor from interacting.

A landmark study shows that bat viruses closely related to SARS-CoV-1 and SARS-CoV-2 emerged far from outbreak sites, pointing to the wildlife trade, not natural bat movement, as the most plausible ...

This activity was supported by Contract No. 28321318D00060015 between the National Academy of Sciences and U.S. Social Security Administration. Any opinions, findings, conclusions, or recommendations ...

During the first few years of the COVID-19 pandemic, the virus SARS-CoV-2 was detected in an increasing number of non-human animal species. This included many wild animal species as well as domestic ...