An international research team has discovered a previously unknown mechanism that plays a key role in the signaling pathways ...

Researchers identified a shared Gβγ signaling pathway driving cardiac fibroblast activation. In cell-based models and animal ...

Plants cannot run away when the wind picks up, rain lashes down or a hungry herbivore begins chewing on their leaves. Instead ...

Cells rely on complex signaling networks in which different molecular pathways communicate with one another. Small GTPases ...

Signal transduction The cellular process that converts a signal, such as a hormone, growth factor, neurotransmitter, cytokine, mechanical force, or environmental cue, into biochemical changes inside ...

Our understanding of how cells interact with each other has been driven for decades by the central concept of ...

Explore how oncogenes and signaling pathways converge and diverge in cancer, shaping diagnostic and therapeutic strategies for personalized interventions. This convergence is accompanied by ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

Acute myeloid leukemia has long been considered a disease that shrugs off glucocorticoids. While these steroid hormones form ...

Idiopathic pulmonary fibrosis (IPF) is a chronic disease in which healthy lung tissue is gradually replaced by scar tissue. While the early events that initiate this change are poorly understood, ...