Instead of having to settle for another field goal, C.J, Stroud and Xavier Hutchinson hooked up to put the 49ers in a deeper hole.

Houston Texans quarterback C.J. Stroud (7) is congratulated by teammates Aireontae Ersery (79) and Tytus Howard (71) after throwing a touchdown pass during the second half of an NFL football game against the San Francisco 49ers Sunday, Oct. 26, 2025, in Houston. Credit: AP/Eric Christian Smith

The 49ers have played some bad football this season. But Sunday was something else entirely: The 49ers played so poorly against the Houston Texans that it makes you question if they can ever win again. Their performance in a 29-15 loss was, in a word, awful.

C.J. Stroud threw for 318 yards and two touchdowns as the Houston Texans controlled both lines of scrimmage in a 26-15 win over the San Francisco

The San Francisco 49ers (5-2) visit the Houston Texans (2-4) Sunday in Week 8. Kickoff from NRG Stadium in Houston, Texas, is at 1 p.m. ET (FOX). Let's analyze BetMGM Sportsbook's NFL odds around the 49ers vs. Texans odds and make our expert NFL picks and predictions for the best bets.

Houston Texans tight end Dalton Schultz collects quarterback C.J. Stroud's outlet pass for a 17-yard catch-and-run gain against the San Francisco 49ers. Houston Texans wide receiver Xavier Hutchinson races down the sideline following a dime over the middle from quarterback C.J. Stroud against the San Francisco 49ers.

Kickoff from NRG Stadium is set for 1 p.m. ET, and the Texans are 2.5-point favorites, according to the latest 49ers vs. Texans odds. The over/under for total points scored is 42. The Texans are -151 money line favorites (risk $151 to win $100),

Ever since Kyle Shanahan took over as the head coach of the San Francisco 49ers, there has been a certain section of fans who have waited for the other shoe to drop.