Mesolimbic dopamine ramps emerge only when overall event rates are high, thereby providing a key constraint on theories of dopamine signaling.

So, the role of the mesolimbic dopamine system in this disorder may go beyond its modulation of motivational reward and into other realms of the brain-behavior connection, but clearly reward ...

Ozempic reduces appetite by interacting with the mesolimbic system, which is also linked to addictive behaviors.