cirm.ca.gov

Cardiac Development at a Single-Cell Resolution.

Mammalian heart development is a complex process. Recent advances in using stem-cell-derived cardiac progenitor cells along with advanced genetic methods are described that will lead to a better ...
cirm.ca.gov

Our Review Process

At CIRM, we aim to keep our grant funding process as simple, clear, and thorough as possible. This guide provides an overview of the process, with links to learn more and contact information for CIRM ...
cirm.ca.gov

Clinical Study of T stem cell memory (Tscm)-based CAR-T cells in Patients with Multiple Myeloma

Translational Candidate s15.BsAb.BCMA-CAR NK cells derived from CD34(+) umbilical cord blood hematopoietic stem cells Area of Impact patients with multiple myeloma ...
cirm.ca.gov

CRISPR activation for SCN2A-related neurodevelopmental disorders.

Serena Tamura, Andrew D Nelson, Perry W E Spratt, Elizabeth C Hamada, Xujia Zhou, Henry Kyoung, Zizheng Li, Coline Arnould, Vladyslav Barskyi, Beniamin Krupkin, Kiana Young, Jingjing Zhao, Stephanie S ...
cirm.ca.gov

Deep learning the dynamic regulatory sequence code of cardiac organoid differentiation.

Eyal Metzl-Raz, Ryan Zhao, Salil Deshpande, Jackson Powell, Elizabeth G Porter, Yassine Zouaghi, Betty B Liu, Samuel H Kim, Immanuel Abdi, Ivy Evergreen, Megha Agarwal, Maya U Sheth, Joshua Rico, ...
cirm.ca.gov

A human-specific regulatory mechanism revealed in a pre-implantation model.

Pre-implantation events in human development are difficult to study due to ethical concerns. This work utilizes a human stem-cell-based blasted model to test the genetic regulation of implantation ...
cirm.ca.gov

CIRM approves over $160M to support preclinical and clinical research, advances education opportunities and access to clinical trials

South San Francisco, CA, December 11, 2025 – The California Institute for Regenerative Medicine (CIRM) governing board today approved funding of over $160 million for 16 new research awards to develop ...
cirm.ca.gov

CIRM Announces Leadership Transition

South San Francisco, CA, Nov. 7, 2023– The California Institute for Regenerative Medicine (CIRM), the world’s largest institution dedicated to regenerative medicine, announced today that Maria T.
cirm.ca.gov

CIRM approves $73 million in awards for discovery research

South San Francisco, CA, September 25, 2025 – The California Institute for Regenerative Medicine (CIRM) has approved awarding more than $73 million across 23 grants to support discovery research ...
cirm.ca.gov

Research Training Grant

The mission of California Institute for Regenerative Medicine (CIRM) is to accelerate stem cell treatments to patients with unmet medical needs. The overall objective of the CIRM Research Training ...
cirm.ca.gov

CIRM awards $27 million to launch novel program designed to bring cell and gene therapies to underserved California communities

South San Francisco, Calif., October 30, 2025 – The California Institute for Regenerative Medicine (CIRM) has approved awarding $27 million through three grants across the state to create a network of ...
cirm.ca.gov

CIRM Announces Recommendations from Strategic Allocation Framework

South San Francisco, CA, September 27, 2024 – The California Institute for Regenerative Medicine (CIRM), one of the world’s largest institutes dedicated to regenerative medicine, announced key ...