San Francisco 49ers wide receiver Jauan Jennings can't hold on to a deep pass attempt from quarterback Mac Jones against the ...

Texans head coach DeMeco Ryans is a former 49ers defensive coordinator under Kyle Shanahan, so San Francisco knows how ...

Kickoff from NRG Stadium is set for 1 p.m. ET, and the Texans are 2.5-point favorites, according to the latest 49ers vs.

San Francisco 49ers TE George Kittle and QB Mac Jones showcased flashes of playmaking during the loss to Houston, highlighted ...

A week after the 49ers earned a 20-10 prime-time home win over the Atlanta Falcons, the Niners’ shorthanded defense was on ...

Next up, the Texans will host the Denver Broncos in an AFC wildcard tilt. Houston is still trying to dig their way back to ...

San Francisco 49ers QB Mac Jones hits WR Demarcus Robinson for a successful two-point conversion in the team's week 8 matchup ...

The San Francisco 49ers dropped their third game of the season on Sunday, falling short 26-15 on the road to the Houston ...

Well, that was ugly. The San Francisco 49ers lost in depressing style to the Houston Texans 26-15. They lost their third game ...

The 49ers have played some bad football this season. But Sunday was something else entirely: The 49ers played so poorly ...