The redemption arc of quarterback Mac Jones was fun while it lasted, but the San Francisco 49ers need starting QB Brock Purdy to return as soon as possible.

Kickoff from NRG Stadium is set for 1 p.m. ET, and the Texans are 1.5-point favorites, according to the latest 49ers vs. Texans odds. The over/under for total points scored is 42. Before you make any Texans vs. 49ers picks, make sure to check out what the SportsLine Projection Model has to say.

San Francisco 49ers wide receiver Jauan Jennings can't hold on to a deep pass attempt from quarterback Mac Jones against the Houston Texans.

The Texans lost to the Seattle Seahawks 27-19 on Monday night even though Anderson scored the first touchdown of his NFL career. Anderson had a strip-sack of quarterback Sam Darnold and recovered the fumble in the end zone.

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San Francisco 49ers tight end Jake Tonges catches a 2-yard touchdown pass on a crossing route from quarterback Mac Jones against the Houston Texans.