Computational models of the glucoregulatory system constitute a powerful tool for preclinical evaluation and mechanistic insight into therapeutics. However, in the case of diabetes, there is a dearth ...

ConspectusPhotovoltaics (PVs) are currently the most economical and location-independent source of electricity generation, and their demand is growing rapidly as a sustainable renewable energy source.

Hybrid small-molecule/protein fluorescent probes are powerful tools for visualizing protein localization and function in living cells. These hybrid probes are constructed by diverse site-specific ...

The regulation of the immune microenvironment is a key component of wound healing, where suitable wound dressings with skin immunoreactivity can favorably affect the immune process and promote the ...

Here, we report a photo- and copper-catalyzed enantioselective oxidation of benzylic C(sp3)–H bonds using N-hydroxyphthalimide as the oxygenated reagent. The reaction proceeds under mild conditions ...

mRNA therapy holds significant promise for preventing and treating diverse diseases. The development of safe and effective cationic polymers for mRNA delivery is essential for advancing its clinical ...

1,2,4-Thiadiazoles, a significant class of heterocyclic compounds, are widely found in biologically active molecules. Herein, we report a green electrochemical three-component reaction of amines, ...

Although the most commonly used method for enhancing a limit of detection (LoD) in immunoassay is adopting chemiluminescence (CL), the liquid form of CL substrates has hindered its use for rapid ...

This review discusses the transformative impact of the convergence of artificial intelligence (AI) and laboratory automation on the discovery and synthesis of metal–organic frameworks (MOFs). MOFs, ...

Nanoaperture optical tweezers allow for trapping single proteins and detecting their conformational changes without modifying the protein, i.e., being free from labels or tethers. While past works ...

A rhodium-catalyzed annulation of 2H-azirines with enaminones is presented. This protocol affords a convenient approach to the diversity-oriented synthesis of 4-acyl- and 4-formyl pyrroles with good ...

The aim of this review is to address the most up-to-date information on the design and development, structure–activity relationship (SAR), and molecular docking study of novel and effective urease ...