The San Francisco 49ers are preparing for their Week 17 contest against the Detroit Lions on Monday at Levi's Stadium in ...

The 49ers will have running back Isaac Guerendo for Monday Night Football. Guerendo, who missed last week's game with a ...

Head coach Kyle Shanahan offered an update on Saturday regarding the recovery of San Francisco 49ers wide receiver Brandon ...

San Francisco 49ers head coach Kyle Shanahan spoke with reporters after Saturday's practice as the team prepares for its Week ...

SANTA CLARA — The 49ers are set to head into their "Monday Night Football" contest with the Detroit Lions a little worse for ...

The San Francisco 49ers entered Sunday's matchup against the Miami Dolphins without two key offensive contributors: running ...

The NFL's much-discussed new rule against hip-drop tackles has only produced one penalty flag this season, against Carolina's ...

San Francisco 49ers running back Isaac Guerendo is expected to return from foot and hamstring injuries and play Monday, a ...

Tight end George Kittle is known for being one of the most upbeat and positive personalities in the San Francisco 49ers ...

The playoff-eliminated San Francisco 49ers are set to host the Detroit Lions on Monday night in a rematch of last season's ...

Detroit's defensive injuries will probably catch up to them in the postseason, but the 49ers don't look to have enough in the ...

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