BACKGROUND: Metabolic adaptation and maladaptation are hallmarks of the failing heart and may be a target for therapeutic ...

Caffeine is one of the most commonly consumed drugs in the world. It is found in various naturally occurring substances and can be ingested in a synthetically derived pure form. The majority of human ...

Explore the latest research and articles in Circulation Research, featuring high-impact studies and reliable findings for the scientific community.

The API-CAT trial (Apixaban Cancer-Associated Thrombosis) demonstrated that, in patients with active cancer who had completed ...

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The ultimate measure of cardiovascular science is not only whether it advances knowledge but whether it meaningfully improves ...

Exercise and physical activity are recognized as essential tools to optimize fitness and longevity, improve overall health, ...

Dual antiplatelet therapy (DAPT) with aspirin and clopidogrel is a cornerstone of early secondary prevention after minor ischemic stroke or high-risk transient ischemic attack (TIA). Current ...

Polypharmacy in patients with cardiovascular disease occurs frequently across the age spectrum and can lead to inappropriate ...

Over the past decade, GLP-1 receptor agonists (GLP-1 RAs) have evolved from niche glucose-lowering agents to one of the most widely discussed drug classes in medicine. Their cardiovascular benefits, ...

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Highlighting essential AHA/ASA journal articles on improving cardiovascular and cerebrovascular health for all. Precision medicine considers an individual's genetics, environment and lifestyle in ...