is a global, peer-reviewed, open access lupus journal from LFA, publishing papers on all aspects of lupus and related diseases.

Objective To apply large language models (LLMs) to Reddit posts referencing SLE to identify patient-expressed unmet medical ...

Objectives To determine the prevalence of cerebral atrophy in a multi-ethnic systemic lupus erythematosus (SLE) cohort and to ...

Introduction Patients with SLE have an increased risk of infections and infection-related mortality, which may be associated ...

Introduction Cognitive symptoms such as ‘brain fog’ are frequent and disabling in patients with SLE. We aimed to develop and ...

Objective To determine the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of subcutaneously administered mosunetuzumab, a CD20xCD3 T-cell-engaging bispecific antibody, in ...

Objective To examine B cell-activating factor (BAFF) and type I interferon (IFN) activity at the transcriptional and protein levels in blood and placental tissue in SLE compared with healthy ...

Objectives To assess indirect costs (IDC) due to lost productivity in paid/unpaid labour, stratified by sex, in a national prospective observational multicentre Canadian SLE cohort. Methods Patients ...

Objective Although current treatment recommendations for systemic lupus erythematosus (SLE) provide the option for biologic agents without prior failure of immunosuppressants (IS), data on this ...

Background Lupus nephritis (LN) is a severe and prevalent complication of SLE. Compound Muniziqi granule (CMG), a traditional remedy, is commonly used to treat immune system-related disorders. However ...

Objective To investigate the effects of Qihuang Jianpi Zishen Granules (QJZG) on renal injury in SLE mice, focusing on macrophage M1/M2 polarisation mediated by the AMPK/ULK1 signalling pathway.