Background Numerous studies have found associations between parental socio-economic position (SEP) and offspring asthma.

Background Risk factors for COPD in high-income settings are well understood; however, less attention has been paid to contributors of COPD in low-income and middle-income countries (LMICs) such as ...

A 13-year-old boy with primary ciliary dyskinesia (PCD) had progressive severe cystic bronchiectasis of the left middle and lower lobes on serial CT scans, in the context of situs inversus totalis and ...

Individuals born extremely preterm (EP-born) must complete lung development outside the uterus, affecting the maturation and growth of airways and alveoli. They often show signs of both obstructive ...

The number of asthma deaths among children and young people (CYP) in the UK has remained stubbornly constant despite advances in medication, delivery systems and maintenance and reliever therapy ...

Correspondence to Distinguished Professor Charlie C Xue, School of Health and Biomedical Sciences, RMIT University, Melbourne, Victoria, Australia; charlie.xue{at}rmit.edu.au; Professor Lin Lin, The ...

Spirometry phenotypes at 8 years in children born extremely preterm or with extremely low birth weight ...

3 The University of Manchester, Manchester Academic Health Science Centre, University Hospital South Manchester NHS Foundation Trust, Manchester, UK 4 University Hospital of South Manchester, ...

Background The Clinical COPD Questionnaire (CCQ) is a simple 10-item, health-related quality of life questionnaire (HRQoL) with good psychometric properties. However, little data exists regarding the ...

2 Department of Pulmonary and Cardiac Rehabilitation, Coventry University, School of Health and Life Sciences, Coventry, UK 3 Clinical Trials Unit, Warwick Medical School, The University of Warwick, ...

Background Despite exacerbations of chronic obstructive pulmonary disease (COPD) being both common and often fatal, accurate prognostication of patients hospitalised with an exacerbation is difficult.

Rationale Recently a frequent exacerbator phenotype has been described in bronchiectasis, but the underlying biological mechanisms are unknown. Antimicrobial peptides (AMPs) are important in host ...