BACKGROUND: Metabolic adaptation and maladaptation are hallmarks of the failing heart and may be a target for therapeutic ...

The API-CAT trial (Apixaban Cancer-Associated Thrombosis) demonstrated that, in patients with active cancer who had completed ...

Caffeine is one of the most commonly consumed drugs in the world. It is found in various naturally occurring substances and can be ingested in a synthetically derived pure form. The majority of human ...

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VESALIUS-CV is a large (N=12 257), rigorously conducted, international, randomized, placebo-controlled trial conducted in patients at high cardiovascular risk but without prior myocardial infarction ...

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Outcomes among patients living alone at stroke onset could be directly affected by reduced access to acute therapies or indirectly through the effects of social isolation. We examined the associations ...

Here, we present a novel preclinical model for IDOL studies, leveraging the advantages of rabbits as models for studying its role in atherosclerosis. We generated IDOL KO rabbits using CRISPR/Cas9 ...

On page e382, in Table 2-4, 2 entries have been updated: In the fourth row (“Opioid use disorders”), fifth column (“2019”), the entry read, “286.80.” It has been updated to read, “2286.80.” In the ...

Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) are effective therapies for glucose‐lowering and weight management. A growing number of therapies within this drug class are now available. 1, 2 ...

Chronic coronary disease (CCD) affects millions of people worldwide and is responsible for significant morbidity, mortality, and costs. CCD as defined in the 2023 guideline 1 includes patients who may ...

Coconut water has become an increasingly popular sports drink because of its natural ingredients, electrolytes, and mineral content. Marketing has focused on the product’s low levels of fat, calories, ...