BACKGROUND: Metabolic adaptation and maladaptation are hallmarks of the failing heart and may be a target for therapeutic ...

Caffeine is one of the most commonly consumed drugs in the world. It is found in various naturally occurring substances and can be ingested in a synthetically derived pure form. The majority of human ...

The API-CAT trial (Apixaban Cancer-Associated Thrombosis) demonstrated that, in patients with active cancer who had completed ...

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Dual antiplatelet therapy (DAPT) with aspirin and clopidogrel is a cornerstone of early secondary prevention after minor ischemic stroke or high-risk transient ischemic attack (TIA). Current ...

A short A-V conduction time, whether present with normal or with abnormal QRS complex, is associated with an increased incidence of paroxysmal rapid heart action. There are a considerable number of ...

Explore the latest research and articles in Circulation Research, featuring high-impact studies and reliable findings for the scientific community.

Highlighting essential AHA/ASA journal articles on improving cardiovascular and cerebrovascular health for all. Precision medicine considers an individual's genetics, environment and lifestyle in ...

The Multiple Risk Factor Intervention Trial (MRFIT) is a randomized primary prevention trial that tested the effect of a multifactor intervention program on coronary heart disease (CHD) mortality in ...