Brock Purdy threw three touchdown passes and the 49ers (10-4) cruised to a 37-24 win over the visiting Tennessee Titans (2-12).

Listed as inactive for the 49ers were wide receiver Jordan Watkins, running back Jordan James, linebacker Nick Martin, linebacker Tatum Bethune, defensive lineman Sebastian Valdez, defensive lineman Sam Okuayinonu and defensive lineman Jordan Elliott. Elliott was a late addition ot the injury report with a knee issue.

The Tennessee Titans dipped into their practice squad to add some reinforcements for their Week 15 matchup with the San Francisco 49ers.

Kyle Shanahan on Brandon Aiyuk being move to the “left team” list: “It’s extremely unfortunate that it has gotten to this point but when this year is over, we’ll see

Tennessee Titans defensive tackle Jeffery Simmons is back in the end zone after his second career touchdown catch, this one against the 49ers.

The Tennessee Titans are back in the loss column after falling 37-24 to the San Francisco 49ers in Week 15 at Levi's Stadium. The Titans were trailing for the e