Dec 23, 2025 · MIT scientists strip cancer of its sugar shield Using new molecules that block an immune checkpoint, researchers from MIT & Stanford showed they could stimulate a strong …

Dec 16, 2025 · Using molecules called AbLecs that block an immune checkpoint, researchers showed they could stimulate a strong anti-tumor immune response. The approach, which …

Aug 5, 2025 · A comprehensive analysis published in Reserch illuminates how cancer cells hijack immune checkpoints on natural killer (NK) cells to disable the body’s frontline defense system.

Dec 23, 2025 · Researchers at the University of Sharjah are exploring a promising approach that could enhance the immune system's ability to fight cancer, potentially paving the way for new …

The present study was initiated by comparing publicly available transcription profiles of tumor tissues from responsive and resistant ICB-treated patients across various cancer types.

Nov 27, 2025 · Recent studies suggest that tumor cells may hijack CD300a-associated pathways to establish an immunosuppressive microenvironment that facilitates immune evasion, tumor …

Immunotherapy has revolutionized cancer treatment by enabling durable tumor control through immune activation. Emerging evidence suggests that beyond …

May 29, 2023 · Tumor-associated macrophages (TAMs) are the predominant immune cells that infiltrate the tumor microenvironment and express a variety of immune checkpoints that impact …

Sep 15, 2025 · In addition, immune-related toxicities, particularly those associated with CTLA-4 blockade, restrict the broader use of these agents. To overcome these barriers, attention has …

5 days ago · The disease stage and the precise location of the tumor determine whether conventional treatment modalities—surgery, chemotherapy, radiation, immunotherapy, and …